Top 100 Medical Equipment Manufacturers in the USA (2026)

Medtronic is the largest medical equipment manufacturer based in the USA, with $36.4 billion in revenue in its fiscal year that ended in April 2026, according to Medical Design & Outsourcing’s 2026 Medtech Big 100. Johnson & Johnson’s MedTech business ($33.8 billion), Medline ($28.4 billion), Stryker ($25.1 billion) and Abbott’s medical devices segment ($21.4 billion) round out the top five. Together, the ten biggest US companies on our list booked about $230 billion, roughly two-thirds of everything the 97 public companies below report.

This ranking covers 100 US-headquartered makers of medical devices and equipment, from billion-dollar heart valve and surgical robot companies to small Florida and Minnesota firms selling MRI-safe infusion pumps or airway clearance vests. Revenue comes from MDO’s October 2026 edition of the Big 100 (mostly calendar 2025 results) and, for US companies below or outside MDO’s cut, from trailing 12-month revenue listed by Stock Analysis. Every row says which period applies. Three private or foreign-owned companies with credible revenue figures sit in a separate group at the end.

Top 100 Medical Equipment Manufacturers in the USA Ranked by Revenue

Ranks 1 to 97 are publicly reported companies sorted by their latest revenue figure. Rows marked FY use the fiscal-year revenue published in MDO’s 2026 Big 100; where a company reports segments, MDO counts only the medtech segment (Abbott, BD, Cardinal Health, Solventum and Plexus). Rows marked TTM use trailing 12-month revenue from Stock Analysis’s medical devices and medical instruments and supplies industry pages, checked on October 31, 2026. Revenue is in US dollars.

*Medtronic and Steris run their businesses from Minneapolis and Mentor, Ohio, but are legally domiciled in Ireland. We include them because their operating headquarters, leadership and largest workforces are in the US.

Private and Subsidiary Manufacturers With Published Revenue

These three companies do not file standalone revenue with the SEC. Each shared a figure with MDO for the 2026 Big 100, which is why they appear here, ranked after the public group. Zoll is based in Massachusetts but has been owned by Japan’s Asahi Kasei since 2012; Cook Medical and Applied Medical are privately held.

The 10 Largest US Medical Device Companies, Profiled

The top ten mixes three very different business models: diversified device makers (Medtronic, J&J MedTech, Abbott), focused specialists (Stryker, GE HealthCare, Boston Scientific, BD) and supply houses that both manufacture and distribute (Medline, Henry Schein, Cardinal Health). That mix matters if you are comparing them as employers, suppliers or customers.

1. Medtronic: The Broadest Device Portfolio in the Industry

Medtronic sells pacemakers, implantable defibrillators, the Micra leadless pacemaker, TAVR valves, spinal cord stimulators, spine hardware and the Hugo robotic-assisted surgery system, among thousands of other products. MDO puts its latest fiscal-year revenue at $36.4 billion, up 8%, and its R&D budget at $2.9 billion, the highest of any company in the 2026 Big 100. In March 2026 it carved out its diabetes unit: MiniMed began trading on Nasdaq on March 6, raising about $560 million, with Medtronic keeping roughly 90%. It also closed its $585 million CathWorks purchase on April 20, 2026 and agreed on May 20 to buy nerve stimulation company SPR Therapeutics for $650 million.

2. J&J MedTech: Orthopedics Is About to Leave

Johnson & Johnson’s device arm reported $33.8 billion for 2025. Its products span DePuy Synthes hip, knee and trauma implants, Biosense Webster electrophysiology catheters, Abiomed’s Impella heart pumps, Shockwave intravascular lithotripsy, Ethicon surgical staplers and Acuvue contact lenses. J&J said in October 2025 it would separate DePuy Synthes, and MD+DI reported in February 2026 that it was also weighing a sale that Bloomberg valued above $20 billion. DePuy Synthes brought in nearly $9.3 billion in 2025, so the MedTech total will shrink sharply once the unit leaves.

3. Medline: The Biggest IPO of 2025

Medline makes and distributes about 335,000 medical-surgical items, from exam gloves and gowns to procedure kits, and produces about a third of its own-brand products in 33 factories. The Northfield, Illinois, company priced its upsized IPO at $29 a share on December 16, 2025, raising $6.3 billion on Nasdaq under the ticker MDLN. MDO lists its revenue at $28.4 billion, which puts a family-built supplier ahead of Stryker and Abbott’s device business.

4. Stryker: Orthopedic Robots and Hospital Gear

Stryker, based in Portage, Michigan, earned $25.1 billion in 2025. The Mako robot for knee and hip replacement anchors its orthopedics franchise, and it also sells neurovascular devices, stretchers, hospital beds and power tools for surgeons. In May 2026 it completed the purchase of Amplitude Vascular Systems for $435 million upfront plus up to $400 million in milestones, adding an intravascular lithotripsy system for blocked arteries.

5. Abbott: CGMs and Heart Devices Drive the Device Segment

MDO counts only Abbott’s medical devices segment ($21.4 billion), which jumped two places to No. 6 globally. Its FreeStyle Libre continuous glucose monitors, MitraClip and TriClip heart valve repair systems, electrophysiology catheters and neuromodulation implants sit in that segment. Abbott’s diagnostics, nutrition and branded drug businesses are excluded. The company completed its acquisition of Exact Sciences on March 23, 2026, a cancer screening deal reported at about $21 billion.

6. GE HealthCare: The Largest US Imaging Manufacturer

Spun off from General Electric in January 2023, Chicago-based GE HealthCare makes CT and MRI scanners, ultrasound systems, X-ray and mammography units, patient monitors and the contrast agents used in scans. Revenue was $20.6 billion in 2025. It closed its $2.3 billion purchase of imaging software maker Intelerad on March 18, 2026, a bet that hospitals will move image storage and reading tools to the cloud.

7. Boston Scientific: Heart Rhythm Devices at Scale

Boston Scientific grew revenue 20% to $20.1 billion in 2025, one of the fastest rates in MDO’s ranking. Its best-known products are the Farapulse pulsed field ablation system for atrial fibrillation and the Watchman left atrial appendage implant. The Marlborough, Massachusetts, company agreed on January 15, 2026 to buy Penumbra for $14.5 billion and in May paid $1.5 billion for about a third of TAVR developer MiRus.

8. BD: A Leaner Company After the Waters Deal

BD makes the syringes, IV catheters and Alaris infusion pumps found in most US hospitals. MDO ranks only its medical and interventional segments, which totaled $18.5 billion in the fiscal year ended September 2025. On February 9, 2026, BD completed the combination of its Biosciences and Diagnostic Solutions businesses with Waters Corp., leaving the Franklin Lakes, New Jersey, company focused on medical devices.

9. Henry Schein: Dental Equipment and Supplies

Henry Schein, based in Melville, New York, reported $13.2 billion. Most of that is distribution to dental and physician offices, though the company also sells its own-brand supplies and dental equipment and practice software, which is why MDO includes it. Frederick M. Lowery became chief executive on March 2, 2026, succeeding longtime leader Stanley Bergman.

10. Cardinal Health: Medical Products Inside a Drug Distributor

Cardinal Health’s total revenue tops $250 billion, but nearly all of it comes from pharmaceutical distribution. MDO ranks only the Global Medical Products and Distribution segment, which makes and distributes Cardinal Health brand gloves, surgical drapes, wound care and patient-handling products. That segment brought in $12.6 billion in the fiscal year ended June 2025, and $12.7 billion in fiscal 2026, according to results released August 11, 2026.

US Medical Equipment Manufacturers by Product Category

We assigned each company to its main revenue category. Diversified giants are counted once, under their own category, even though Medtronic alone competes in several of the others. Combined revenue mixes fiscal-year and TTM figures exactly as listed in the main table.

Surgical robotics looks small when only pure-play makers are counted. In practice it is one of the most contested areas on the list: Medtronic (Hugo), Stryker (Mako), Zimmer Biomet (ROSA), Globus (ExcelsiusGPS) and J&J all sell or are developing robotic systems that compete with Intuitive’s da Vinci. Diabetes is a similar story, with Abbott’s FreeStyle Libre counted under Abbott’s diversified total rather than in the diabetes row.

Home medical equipment is where most of the list’s smaller companies live. Inogen’s portable oxygen concentrators, Tactile’s lymphedema pumps and Electromed’s SmartVest are sold to patients through home care channels, often under Medicare’s durable medical equipment benefit. Readers thinking about selling into that market can find starting points in our guide to medical supply business ideas.

Which States Have the Most Medical Device Manufacturers

California leads by a wide margin, with Southern California’s Orange County and San Diego clusters and the Bay Area together accounting for 31 of the 100 companies. Massachusetts, home to Boston Scientific, Insulet and a cluster of Burlington and Marlborough firms, is second with ten.

Revenue tells a different story from company counts. Illinois has just four entries but leads on combined revenue, and New Jersey’s seven companies outrank California’s 31 because J&J MedTech and BD are both based there. Minnesota’s Medical Alley around Minneapolis punches above its count with Medtronic, Solventum’s MedSurg business and Inspire. Indiana’s Warsaw is home to two companies on the list, Zimmer Biomet and OrthoPediatrics.

For job seekers, those clusters matter more than headquarters addresses. Medical device manufacturing sits within the broader healthcare sector that federal projections expect to keep adding jobs, as covered in our look at the fastest growing industries in the US. If benefits are part of your search, our list of companies with paid parental leave is a useful cross-check.

Deals Reshaping the Medical Equipment Industry in 2026

A ranking built on 2025 numbers is already partly out of date because of the volume of deals. These are the changes most likely to move companies on next year’s list:

• Hologic went private: Blackstone and TPG completed their buyout in April 2026 at $76 a share in cash plus a contingent value right worth up to $3, and former Baxter chief Joe Almeida became CEO. Hologic keeps its rank here because its fiscal 2025 revenue was publicly reported.
• Masimo joined Danaher: The $9.9 billion deal closed June 10, 2026. MDO notes Masimo may not appear in its 2027 ranking.
• Penumbra is heading to Boston Scientific: The $14.5 billion purchase was still pending at the time of writing, with completion expected in 2026.
• Avanos and Integer are going private: Avanos accepted a $1.27 billion offer from American Industrial Partners in April 2026, and Integer plans to sell to KKR for $5.7 billion, possibly closing by the end of 2026.
• Teleflex shrank: Its revenue fell 35% in MDO’s ranking after it sold its acute care, interventional urology and OEM businesses for $2 billion, which dropped it from No. 41 to No. 55 globally.
• Owens & Minor dropped off: The Mechanicsville, Virginia, company was No. 13 on MDO’s prior list but did not share results for 2026, so it is not ranked here.

How This Medical Equipment Manufacturer Ranking Was Built

• Starting list: We took every US-headquartered company from MDO’s 2026 Medtech Big 100, published October 13, 2026. MDO ranks OEMs and the medtech segments of diversified companies by revenue, mostly calendar 2025 results, with some fiscal years ending as late as April 2026.
• Filling ranks below MDO’s cut: MDO’s 100th company, Si-Bone, reported $200.9 million, and only 54 US companies made the global list. For the rest, we used US-headquartered device and equipment makers from Stock Analysis’s medical devices and instruments and supplies industry lists, using trailing 12-month revenue. A handful of these, such as Varex Imaging and UFP Technologies, are large enough to rank between MDO entries.
• Headquarters rule: A company qualifies if its operating headquarters is in the US. Foreign-headquartered companies with big US operations, such as Siemens Healthineers, Philips, Alcon, Smith+Nephew, LivaNova and Novocure, are excluded.
• What is left out: In line with MDO’s scope, pure laboratory diagnostics and life science tools companies (Danaher, Thermo Fisher, Bio-Rad, QuidelOrtho), drug-packaging makers such as West Pharmaceutical Services, and equipment rental or home care service providers such as AdaptHealth are not ranked. Private companies appear only when a credible revenue figure has been published.
• Segments: For Abbott, BD, Cardinal Health, Solventum and Plexus, only the medical device or medical products segment counts, following MDO.

Medical Equipment Manufacturers in the USA: Common Questions

What Is the Largest Medical Device Company in the United States?

By revenue, Medtronic, with $36.4 billion in the fiscal year ended April 2026. It runs the business from Minneapolis but is legally domiciled in Ireland. Counting only companies incorporated in the US, Johnson & Johnson’s MedTech segment ($33.8 billion for 2025) is the largest.

Which State Has the Most Medical Equipment Manufacturers?

California, with 31 of the 100 companies on this list, including Intuitive Surgical, Edwards Lifesciences, ResMed and Dexcom. Massachusetts is second with 10, followed by Minnesota, New Jersey and Florida with seven each.

Is Medline a Manufacturer or a Distributor?

Both. Medline distributes around 335,000 products and makes about a third of its own-brand items in 33 factories, according to Renaissance Capital’s IPO summary. MDO ranks it third worldwide among medical device businesses.

Who Makes the Most Surgical Robots in the US?

Intuitive Surgical of Sunnyvale, California, maker of the da Vinci system, is the largest company whose main business is surgical robots, with $10.1 billion in 2025 revenue. Medtronic, Stryker, Zimmer Biomet and Globus Medical also sell robotic systems.

Which US Companies Make Home Medical Equipment?

On this list, ResMed (CPAP machines), Inogen (portable oxygen concentrators), Tactile Systems (lymphedema pumps), Electromed (airway clearance vests), KORU (home infusion pumps) and Owlet (infant monitors). Medline and Cardinal Health also make home-care supplies.

Medtech Big 100 Rankings and Stock Analysis Revenue Lists

• Medical Design & Outsourcing: 2026 Medtech Big 100, the world’s largest medical device companies
• Medical Design & Outsourcing: 2026 Medtech Big 100 breaks $500 billion (October 13, 2026)
• Stock Analysis: Medical Devices industry list (revenue, accessed October 31, 2026)
• Stock Analysis: Medical Instruments & Supplies industry list (revenue, accessed October 31, 2026)
• MedTech Dive: Top 10 medtech deals in the first half of 2026 (July 6, 2026)
• Renaissance Capital: Medline prices upsized IPO at $29
• HPN Online: Medtronic spinoff MiniMed raises $560M in Nasdaq IPO
• MLO: Hologic announces completed acquisition and new leadership
• Abbott: Abbott completes acquisition of Exact Sciences (March 23, 2026)
• HLTH: Abbott closes $21B deal for Exact Sciences
• MD+DI: J&J rumored to be considering sale of orthopedics unit
• BD: BD completes combination of Biosciences & Diagnostic Solutions business with Waters
• GE HealthCare: GE HealthCare completes Intelerad acquisition
• MarketScreener: Henry Schein appoints Frederick M. Lowery as CEO
• Cardinal Health: Fourth quarter and fiscal 2026 results (August 11, 2026)

More company rankings and industry coverage: Business News.